By the 'Prezi-like animation' I mean that your canvas rotate/zoom/shift to the tiny little portion in a sequential manner.
P.S.: The question is not limited to AE. Any animation sw would be relevant.
Some suggest HTML5, but that targets web design (my purpose is only creating some animation for self entertainment.)
Yes.
You could do it manually. A little tedious, but you would place your text layers in 3d space and push your camera around. You will spend a lot of time tweaking everything like the things in the visible things in the background and the easing moves into and away from the text.
Sure Target is free and could be a big time saver. You basically use it to square up the camera to null objects and it takes a lot of the tedium out of the process, even though you have to spend a few minutes up front to figure out how it works.
http://www.videocopilot.net/tutorial/energetic_titles/