I created a uwsgi file following this tutorial https://uwsgi.readthedocs.org/en/latest/Upstart.html on amazon linux. Though It doesn't seem to run as Nginx just says bad gateway. If I run the
/etc/init/uwsgi.conf
description "uwsgi tiny instance"
start on runlevel [2345]
stop on runlevel [06]
exec /home/ec2-user/venv/bin/uwsgi --ini /home/ec2-user/uwsgi-prod_demo.ini
if I do run the following in shell, then python application runs.
/home/ec2-user/venv/bin/uwsgi --ini /home/ec2-user/uwsgi-prod_demo.ini
uwsgi-prod_demo.ini
[uwsgi]
socket = :8080
chdir = /home/ec2-user/prod_demo
master = True
venv = /home/ec2-user/venv
callable = app
wsgi-file = /home/ec2-user/prod_demo/manage.py
enable-threads = True
https = =0,/home/ec2-user/xxx.com.au.pem,/home/ec2-user/newkey.pem,HIGH
nginx.conf
user  ec2-user;
worker_processes  1;
error_log  /var/log/nginx/error.log;
#error_log  /var/log/nginx/error.log  notice;
#error_log  /var/log/nginx/error.log  info;
pid        /var/run/nginx.pid;
events {
    worker_connections  1024;
}
http {
    include       /etc/nginx/mime.types;
    default_type  application/octet-stream;
    log_format  main  '$remote_addr - $remote_user [$time_local] "$request" '
                      '$status $body_bytes_sent "$http_referer" '
                      '"$http_user_agent" "$http_x_forwarded_for"';
    access_log  /var/log/nginx/access.log  main;
    sendfile        on;
    #tcp_nopush     on;
    #keepalive_timeout  0;
    keepalive_timeout  65;
    #gzip  on;
    # Load modular configuration files from the /etc/nginx/conf.d directory.
    # See http://nginx.org/en/docs/ngx_core_module.html#include
    # for more information.
    include /etc/nginx/conf.d/*.conf;
  server {
    listen 80;
    listen 443 ssl;
    ssl_certificate /home/ec2-user/xxx.com.au.pem;
    ssl_certificate_key /home/ec2-user/newkey.pem;
    server_name import.xxx.com.au  *.import.xxx.com.au;
    access_log /var/log/prod_demo/access_log;
    root /home/ec2-user/prod_demo;
    location / {
      uwsgi_pass 127.0.0.1:8080;
      include uwsgi_params;
    }
    location /static {
         alias /home/ec2-user/prod_demo/app/static;
    }
    location = /favicon.ico {
            alias    /home/ec2-user/prod_demo/app/static/images/favicon.ico;
    }
  }
}
				
                        
To fix this I did a few things. - Moved all scripts from the home directory to an /var/www/ - created an www group and www user and chown /var/www to www:www
Full Instructions
Create a user and group www and www
create a dir where your flask application will be ie /var/www/
/etc/nginx/nginx.conf
/etc/init/uwsgi-prod-demo.conf
/var/www/uwsgi-prod_demo.ini