I have a simple client server program and the server side works but for some reason I can't get the the client to interact to the server.  I am able to launch the server and use nc -u ::1 50007 and connect to it and it works as intended.  
Server code:
import socket
import sys
def main():
    HOST = '::1'
    PORT = 50007
    res = socket.getaddrinfo(HOST, PORT, socket.AF_UNSPEC, socket.SOCK_STREAM, 0, socket.AI_PASSIVE)
    af, socktype, proto, canonname, sa = res[0]
    try:
        s = socket.socket(socket.AF_INET6, socket.SOCK_DGRAM)
        s.bind(sa)
        while True:
            data, addr = s.recvfrom(1024)
            if not data:
                break
            print 'server received %r from %r' % (data, addr)
            s.sendto(data, addr)
        s.close()
    except socket.error, msg:
        print msg
if __name__ == '__main__':
    main()
Client code:
import socket
import sys
def main():
    HOST = '2015:cc00:bb00:aa00::2'   
    PORT = 50007              
    res = socket.getaddrinfo(HOST, PORT, socket.AF_UNSPEC, socket.SOCK_STREAM)
    af, socktype, proto, canonname, sa = res[0]
    try:
        s = socket.socket(socket.AF_INET6, socket.SOCK_DGRAM)
        s.connect(sa)
        s.send('Hello, world')
        data, addr = s.recvfrom(1024)
        s.close()
        print 'Received', repr(data)
    except socket.error as e:
        print e
if __name__ == '__main__':
    main()
I am able to ping from client to server, but I can't nc -u 2015:cc00:bb00:aa00::2 50007 either.  When I run the client code I get a connection refused error. Not sure why it is not connecting, any ideas?
                        
The problem is that your server is listening on localhost
::1but you are trying to connect to2015:cc00:bb00:aa00::2which is a different Interface. Try settingHOST = "::"in your server in order to have it bind to all interfaces.